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The influence of vincristine on mitochondria is thought to involve altered mitochondrial calcium signaling, and the maintenance of intracellular calcium homeostasis is beneficial for preventing CIPN [51, 52]

Production of TMAO TMAO is formed via a two-step process, the meta-organismal diet/microbiota dependent pathway and human endogenous pathway

These preferences and aversions result in restricted diets that may lack nutritional balance, highlighting the need for caregivers and healthcare professionals to develop strategies to gradually introduce new foods and ensure adequate nutrition for individuals with ASD[11]