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168 Recent studies also show that knocking down PPAR coactivator 1 (PGC1), an important transcriptional coactivator regulating CPT1A and CPT1B, obviously decreases the ratio of NADPH/NADP + and ATP levels, impairing radiation resistance in nasopharyngeal carcinoma (NPC) cells

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doi: 10.1016/S0896-6273(02)00653-0