DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 leading to strong intramolecular charge

leading to strong intramolecular charge transfer and a large fluorescence shift (from ~430 nm to ~520 nm)

& Johnsson

Product Name Thalidomide-O-acetamido-PEG1-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG1-C2-acid CAS Number 2204225-99-8 Related CAS Molecular Formula C20H21N3O9 Molecular Weight 447

Product Name CA-Vbn Synonyms Vinylbenzoyl-Halo

334 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 leading to strong intramolecular chargeSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further