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T cells from p47 phox/ mice have the diminished expression of T-bet, STAT-1, and STAT-4 transcription factors and the lowered production of IL-2, IL-4, IFN, TNF, and GM-CSF [66]

Samples were randomized and analyzed on a Q-Exactive Plus hybrid quadrupole-Orbitrap mass spectrometer coupled to an UltiMate 3000 UHPLC system (Thermo Scientific)

The gray value of the band obtained after western blot analysis was scanned and determined using AlphaEaseFC 6.0 image analysis software

Other examples of pathological conditions clearly linked to ferroptosis as well as redoxins include neurodegeneration [191-193] , neuroinflammation and other inflammatory diseases [194,195] , ischemia/reperfusion [196,197] , diabetes mellitus [198,199] , and iron-related diseases such as Friedreichs Ataxia [200,201]