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At present, few studies on the direct relationship between DR and ferroptosis are available, but a recent study has confirmed that ferrous ions play a major role in retinal damage, rather than iron ions [5], which is completely in accordance with the ferroptosis mechanism

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Am J Physiol-Lung Cell Mol Physiol 318(2):L296L303 Yosri H, Elkashef WF, Said E, Gameil NM (2017) Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model

doi: 10.1038/s41598-021-93003-3 58 ZhangHKongWZhaoXXieYLuoDChenS