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Neuroimaging and biomarker studies have provided mechanistic insights into this association

Limited data available suggests that dose adjustment of Polybion A Injection may not be needed in these patients

Dong J, Xiao D, Zhao Z, Ren P, Li C, Hu Y, Shi J, Su H, Wang L, Liu H, Li B, Gao P, Qing G (2017) Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism

The term thiamine-responsive refers to the observation of clinical, symptomatic improvement after administration of high doses of thiamine (86, 87)

This sets the stage for the holistic consideration of factors that go beyond merely addressing symptoms