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Moreover, the inhibitory activity against GST would be predicted to further induce mite death, and the different IC 50 values likely stem from the different substituents at the 2-position in these quinones

HCN4 is a primary component of the sinoatrial node current, accounting for 70%80% of the If current, and is implicated in various cardiovascular conditions, including sinoatrial node dysfunction and arrhythmias (Schweizer et al., 2014)