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Ondansetron is a selective serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery

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Yu J, Zhang Y, Ye Y, DiSanto R, Sun W, Ranson D, et al

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In addition to liver-derived serum IGF-1 (endocrine), there is strong evidence that locally expressed IGF-1 (autocrine/paracrine) regulates longitudinal bone growth in the growth plate [87,127132]

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Future research should investigate the synergistic impact of different RCD modalities on AML stem cell maintenance, chemoresistance and microenvironmental remodeling in order to enable the development of personalized therapies that precisely target death pathways

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