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Congestive Heart Failure: Phentermine can exacerbate symptoms by putting additional pressure on an already struggling heart

[PubMed: 28977620] 16

For example: Folate (B9) Depletion: Excess B12 may reduce folate absorption, leading to hyperhomocysteinemiaa condition linked to oxidative stress and follicle damage

But unlike some of the more famous female hormones like progesterone or estrogen its not always there, hanging out in your body in fluctuating amounts