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doi: 10.1111/j.1439-0396.2011.01231.x 30

& McGettigan, S

PMID 26875845

Evidence suggests that IFN- suppresses System Xc transcription by activating the JAK-STAT-IRF1 pathway, which depletes intracellular GSH stores, intensifies lipid peroxidation, and induces ferroptosis in various tumor and immune cells