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10.1046/j.1471-4159.2003.01674.x 301 YagamiT.UedaK.AsakuraK.SakaedaT.NakazatoH.KurodaT.et al

The role of the endocannabinoid system in the gut has been studied extensively and it is now well-established that cannabinoids modulate gastrointestinal motility, secretion and inflammation

the phrase "therapeutically effective" is intended to qualify the amount of magnesium valproate hydrate for use in the orally or intravenously administered therapy which will achieve the goal of providing a biologically available (i.e., bioavailable) concentration of the drug valproate to effect reducing or preventing, for example, a neurological, immunological, or viral- related disorder, while avoiding adverse side effects typically associated with valproic acid, sodium valproate compositions, or other valproate salts

Therefore, considering the general role of glyoxalases in stress adaptation and the ability of Sorghum bicolor to withstand prolonged drought, the sorghum glyoxalase pathway warrants an in-depth investigation with regard to the presence, regulation and distribution of glyoxalase and D-LDH genes