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Availability: InStock
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Description

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism

Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotides, ISIS 301012, targeting human apolipoprotein B-100

In proximal tubule cells, glutamine is converted to ammonia by the action of glutaminase 1 and glutamate dehydrogenase in the mitochondria and secreted into the tubular lumen [50]