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Meaning: Combining microneedling with exosome therapy is a promising, minimally invasive approach for improving pore size and skin texture, offering safe and long-lasting results in aesthetic dermatology

2.12 Bodipy (581/591)-C11 and MitoTracker deep red FM staining Bodipy (581/591)-C11 (Invitrogen, U.S.A.) and MitoTracker Deep Red FM were used to detect lipid peroxidation and mitochondrial localization, respectively

Under diabetic conditions, DAG accumulation occurs through multiple pathways

4.13.2 Mechanical stress Mechanical testing demonstrates increased tissue stiffness that limits adipocyte expansion and triggers mechanotransduction through focal adhesion complexes (327, 328)