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Typically, it manifests clinically either as solitary or multiple dark melanotic macules (Figure 2a, b) or as diffuse brownish or brown-black areas of melanin hyperpigmentation (Figure 3)

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Studies carried out in CD patients with different clinical features have shown an alteration of microRNA expression in comparison with healthy subjects

one is there's not 8:54 am that many people who become infected by this, but in the past, mortality rate has been really high