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successfully designed and synthesized Fe 3 O 4 @Au-DEX-CP-FA multifunctional nanoparticles ( Transferrin receptor (TfR) is highly expressed on the surface of various cancer cells, which provides a theoretical basis for TfR-mediated targeted drug delivery by Tf-modified nanoparticles ( In addition, mannose receptors (MR) and EpCAM (epithelial cell adhesion molecules) are also effective targets for CRC treatment ( The surface of NDDS can be conjugated with targeting moieties such as antibodies or ligands to specifically bind overexpressed receptors on target cell surfaces, thereby facilitating drug internalization and avoiding off-target effects

This will equate to about 30 million Americans and has already contributed to a labor shortage in the U.S

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Other well-known peptides do remain restricted, including the growth-hormone-type compounds GHRP-2, GHRP-6, and MK-677

However, compared with the placebo, it decreased the average pain score and fatigue in CIPN patients [159]