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pneumoniae have evolved sophisticated strategies that manipulate macrophage defense mechanisms in their favor, enabling survival and replication within the host

Effect of aldosterone and MR blockade on the brain and the kidney

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Exposure to pristane causes lupus-like disease that is characterized by interferon(IFN)-I-dependent autoantibody production, inflammatory cytokines and renal diseases in susceptible mouse models ( Induction of pristane-induced autoantibodies has been shown to be dependent on the inflammatory cytokines as protective effects on nephritis and autoantibodies were observed in INF- / , IL-6 / , IL-12 / , and IL-17 / mice ( Silica Among the environmental and occupational agents associated with immune dysregulation, silica is considered a notable risk factor due to its widespread exposure