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on the other hand, by upregulating the expression of the pro-apoptotic proteins, the Bcl-2 family of proteins, which together induce apoptosis ( Citrus unshiu peel (Chen pi) water extract (CUP) upregulated the expression of anti-apoptotic proteins Bcl-2 and Survivin by significantly inhibiting the expression of pro-apoptotic proteins Bax and caspase-3 in colonic tissues

Martin, R., Sospedra, M., Eiermann, T

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