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Description

Similar to selective autophagy, the ubiquitination of impaired lysosomes is the major factor driving and modulating lysophagy 55

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Nrf2 up-regulates transcription of autophagy-associated genes, such as Atg5 , p62 , and others

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Thus, cystine and GSH cooperate to suppress lipid ROS and ferroptosis in HepG2 cells

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