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Oxidative status of participants was determined by the total oxidative stress (TOS) of their samples and the assessment of thiobarbituric acid reactive substances (TBARS) as MDA and also the assessment of nitric oxide (NO) levels

However, we are yet to reach the desirable Technology Readiness Level to adopt these tools in a real-life clinical setting (Ganguly et al., 2021)

Specifically, FXR activation modulates glucose and lipid metabolism by reducing the expression of key enzymes involved in gluconeogenesis and lipogenesis

This finding has renewed interest in the application of dysregulated Cu homeostasis in diseases

Moreover, current treatments of CPP disease are only symptomatic and not able to dissolve CPP crystals