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Administration of the synthetic peptide A1228P, structurally akin to the ApoE binding site on full-length A, has exhibited a reduction in insoluble tau accumulation in AD mouse models (Liu et al., 2014)

[DOI] [PubMed] [Google Scholar] 144.Dwyer J.T., Saldanha L.G., Bailen R.A., Bailey R.L., Costello R.B., Betz J.M., Chang F.F., Goshorn J., Andrews K.W., Pehrsson P.R

Several of these drugs exhibit direct or indirect effects on EC metabolism, which is increasingly recognized as central to vascular aging and atherosclerosis

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With numerous scientific studies available, it can be challenging for doctors to identify the best treatments for their patients