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Further, work by Ji et al

Reduced irritation may improve range of motion and exercise execution

10.1023/B:JOBB.0000041755.22613.8d 67 DebelaD

Similarly, mTORC1 also regulates purine biosynthesis by regulating the levels of MTHFD2 (mitochondrial tetrahydrofolate cycle enzyme methylenetetrahydrofolate dehydrogenase 2) via the transcription factor ATF4 (cyclic AMP-dependent transcription factor ATF-4) (Duvel et al., 2010)