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Annual Review of Nutrition

Intriguingly, another interesting research lead to the discovery of a differential role for IRSs in apoptosis, suggesting an antiapoptotic effect for IRS-2 [122] which is consistent with known differential roles of IGF-1 and insulin

The peptide also increases elastin production by 30% and dramatically upregulates decorin, a proteoglycan that regulates collagen organization

Early data also suggest its benefits for lowering cholesterol levels, liver fat reduction, and cardiovascular health protection

Absence of Common Growth Hormone Side Effects: Because AOD-9604 does not bind to growth hormone receptors or elevate IGF-1, it avoids edema and fluid retention, joint pain and stiffness, carpal tunnel syndrome, glucose elevation and insulin resistance, increased cancer risk concerns from IGF-1 elevation, organ growth or acromegaly features with long-term use, and thyroid function suppression