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In animals, sleep deprivation also leads to upregulation of -secretase 1 (BACE-1), the most important enzyme regulating A generation in the brain 142,143,149 , thus opening the hypothesis of increased A production by sleep deprivation

10.1016/j.jep.2024.118425 [DOI] [PubMed] [Google Scholar] Hu S., Li A., Huang T., Lai J., Li J., Sublette M

Dysfunction of this system can contribute to increased oxidative stress and the progression of MASLD [174]

Furthermore, EGCG attenuates excessive levels of NO generated by inducible nitric oxide synthase (iNOS) (65)

Three trained panelists evaluated the diluted extracts using an olfactometric port attached to the GCMSO system