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BMC Infect Dis (2012) 12:13

In animal models, SFN appears to be a promising adjunct therapy for SZ, mitigating side effects such as metabolic defects, biochemical imbalances, and liver histological abnormalities associated with olanzapine (OLA) (El-Shoura et al., 2024)

By modulating both glutamatergic and GABAergic signaling, these compounds stabilize synaptic communication and mitigate neuronal hyperexcitability commonly associated with depressive phenotypes