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89 Despite showing hallmarks of ferroptosis (excess iron and lipid peroxidation), mice treated with deferiprone experienced an exacerbated ischemic reperfusion injury to hindlimb muscle

And the chemical imbalance theory has not actually been clinically proven

Its impedance-matched 13.56 MHz signal with low-frequency modulation synergizes thermal metabolic disruption and non-thermal immunogenic cell death, demonstrating superior clinical outcomes over conventional hyperthermia

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and Davidson, E.H., "Cis-regulatory control of the nodal gene, initiator of the sea urchin oral ectoderm gene network", Developmental Biology 306: 860-869 (2007)