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211 Combination therapy For people newly diagnosed with T2D, there are two approaches to pharmacal therapy: stepwise therapy and combination therapy

Anticipation and entrainment to feeding time in intact and SCN-ablated C57BL/6j mice

992,993 Future work should explore the roles and clinical uses of MCT1 inhibitors and their potential synergistic combinations with other therapies

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For example, the common antifungal agent, ketoconazole (NIZORAL), is a potent inhibitor of CYP3A4 and other CYPs, and coadministration of ketoconazole with an anti-HIV viral protease inhibitor reduces the clearance of the protease inhibitor and increases its plasma concentration and the risk of toxicity