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[DOI] [PMC free article] [PubMed] [Google Scholar] 314.Elhassan, Y

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Song NJ, Choi S, Rajbhandari P, Chang SH, Kim S, Vergnes L, Kwon SM, Yoon JH, Lee S, Ku JM, Lee JS, Reue K, Koo SH, Tontonoz P, Park KW

It attaches partially to beta-3 adrenergiclinked pathways in fat tissue, which activates lipolysis and fat breakdown without influencing appetite, blood glucose or CNS signals

doi: 10.1073/pnas.0903898106

The compound's selectivity profile minimizes concerns about off-target effects, but investigators should consider potential interactions with other NAD+-modulating interventions or compounds that affect methylation metabolism