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However, we will be looking forward to novel local and systemic mechanisms, molecules and agents that would be able to improve this concept by pharmacological therapy

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[] Although the optimal rate of weaning is not yet identified, there is an approach that could be used for a long weaning process to prevent and treat benzodiazepine-induced withdrawal symptoms, which involves using long-acting agents like diazepam, chlordiazepoxide, or clonazepam in maintenance therapy