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Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

Sur le plan scientifique, ces deux effets reposent sur des mcanismes distincts

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Hepatic steatosis, insulin resistance, and systemic inflammation all significantly improve as a result of the substantial and long-lasting weight loss brought about by bariatric surgeries[97]