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Severe gastroparesis may worsen with GLP-1 agonist use

Modeling spine calcium transients [edit] Calcium transients in spines are a key trigger for synaptic plasticity

10.1038/nn.4328 272

Also, crosstalk with other signaling pathways such as transforming growth factor-beta (TGF-) has led to carcinogenesis and resistance to targeted therapies in human lung, pancreatic, and breast tumor xenografts [17]