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Korac B, Kalezic A, Pekovic-Vaughan V, Korac A, Jankovic A (2021) Redox changes in obesity, metabolic syndrome, and diabetes

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An example of where this phenomenon has been shown to occur is in the dog prostate with toenail selenium concentrations, which are a good indicator of long-term selenium status1

While NM loss is localised only to the SN and LC in PD, increases in brain tissue iron concentration in PD relative to controls are seen throughout the brain using QSM 60,61,62 , most commonly in the basal ganglia

If Vitamin B12 deficiency remains untreated, it can have significant long-term negative effects on the neurological system and brain