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IV daratumumab was demonstrated in RRMM patients for monotherapy in the Phase III COLUMBA trial ( 3 prior lines) and in standard combination regimens in the Phase II PLEIADES trial ( 1 prior lines) [14]

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Although there was no significant correlation between cell growth status and gss gene overexpression level, the maximum cell density and maximum specific growth rate data of the two main cell growth characteristics were significantly higher in the overexpression cell lines compared to the control cell lines (Table 2)

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