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Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, et al

In wild-type mice, FGF21 treatment increases hepatic transcription of the canonical oxidative stress response and antioxidant genes Sod2 (superoxide dismutase 2), Cat (catalase), Gpx1 (glutathione peroxidase 1), Sirt1 (sirtuin), and Foxo3 (forkhead box transcription factor 3) (151)

Within the brain, there is the most selenoprotein expression in the olfactory bulb, cerebral cortex, hippocampus, and cerebellar cortex (Zhang et al., 2008), and selenium is transported to these areas by SELENOP (Hill et al., 2003

These results indicate that combined stimulation of the NAc and ALIC is a promising stimulation strategy for DBS treatment of addiction, which is in line with the findings of previous studies [24, 26]

This synergistic combination effectively suppresses HIV replication, thereby reducing viral load and preventing the progression of HIV infection to AIDS