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For activation of the Mitogen activated protein kinase (MAPK) cascades, c-MET activation stimulates the activity of the rat sarcoma viral oncogene homolog (RAS) guanine nucleotide exchanger Son of Sevenless (SOS) via binding with SHC and GRB2 [Graziani et al

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View image online ( Bottle of vitamins and oversized capsule of vitamin B, with oversized heart in background Niacin, aka vitamin B3, is sold as a supplement and in higher doses as a prescription drug