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In future trials it will be important to keep track of comorbidities for clinical trial design, either for the purpose of post hoc subgroup analysis or a priori subgroup recruitment, since the neuroathophysiological mechanisms in IC/ BPS patients with different co-morbidities are likely to be different

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We summarize the specific proteins and pathways discussed in cell migration and correlate their functional roles in the context of fibrosis

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NAC vs Glutathione Its important to highlight that NAC supports, replenishes and is a precursor for Glutathione