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Parenteral administration is typically used to treat vitamin B12 deficiency caused by pernicious anemia as well as other conditions (e.g., tropical sprue, pancreatic insufficiency) that result in vitamin B12 malabsorption and severe vitamin B12 deficiency

Formation of a vasoactive nitric oxide donor

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Although urine, stool, or volatile samples can be collected in a non-invasive way, the time of elimination has an impact on the degradation of the microbial products, which may have an impact on the analysis (79)