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compounded formulations with enhanced penetration vehicles offer an alternative for patients who cannot tolerate or prefer to avoid systemic antifungals

However, this proposal presents a conflict between meeting sustainable urban development needs and ensuring flood safety, as much of the surrounding land may fall within the newly designated floodplain, severely restricting its potential for development and regeneration

For these reasons, we do not believe that a patient's previous consent for CCM would be sufficient for purposes of the new APCM services, and a beneficiary transitioning from CCM to APCM would require a new consent

The compound exists in an interesting regulatory position

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