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306 Though numbers of clinical trials have suggested that mipomersen has efficacy in lowering ApoB-related lipoproteins in patients with different hypercholesterolemic phenotype, its approval is currently only available to treat homozygous familial hypercholesterolemia as an adjunctive orphan drug due to adverse effects such as flu-like symptoms and transaminitis

abnormal ironsulfur clusters lead to deficiencies in target proteins, including complexes I, II, and III

For example, multi-strain probiotics have demonstrated greater efficacy than single strains for treating IBS [53, 54]

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although the HK diet significantly attenuated blood pressure in male rats, their pressure was still elevated and was not lowered sufficiently to reduce renal damage