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Our initial attempt to create a plasmid based on the biotin ligase BirA backbone (Eric Campeau, Addgene plasmid #26624) was unsuccessful

Eur J Pharmacol (2015) 757:110

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for instance, DON can significantly reduce the transepithelial electrical resistance (TEER)(Grenier and Applegate, 2013)

In the latter study, M6G was 17 times more potent than morphine when these drugs were administered in the cerebral ventricles, but less potent when injected subcutaneously