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The primary safety concern with compounded lipotropic preparations is variability in formulation quality and sterility , as compounding pharmacies operate under different regulatory standards than pharmaceutical manufacturers

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Of the CTBP1 and CTBP2 isoforms, only CTBP2 knockout mice showed severe developmental defects, dying by E10.5 from problems with extra-embryonic development, whereas the CTBP1 mutants were viable, although smaller 188