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It is worth to mention that available reports describing the encapsulation of GSH- or albumin-protected AuNCs are limited to hydrophilic, rather than hydrophobic, matrices such as nanogels 25 , aqueous core of microcapsules 26 , silica nanoparticles, protein nanoparticles 27,28 , polymer nanoparticles 29,30 and metal-organic frameworks 31

This is different from steroid hormones, which are lipid-based and can enter cells to influence gene expression more directly

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Rather, Yeungnam University, Republic of Korea Reviewed by Tahani Bakhsh, University of Jeddah, Saudi Arabia Laiba Arshad, Forman Christian College, Pakistan Updates Copyright 2023 Tian, Huang, Fu, Gao, Mi, Bai, Ma, Zhang, Lu, Zhao, Zhang, Jiang, Lin, Yue, Yuan and Meng

8, 9 Despite these consequences, many people believe that gout is only treated with short-term analgesics for flares, or that nothing can be done at all