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Indeed, defects in B cell check points have been shown to be associated with the development of multi-reactive autoantibodies in patients with systemic lupus erythematosus or rheumatoid arthritis (96)

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[PubMed] 49: Klein R., Klein B.E.K., Moss S.E

[PubMed] [Google Scholar] 7.Wang C.C., Xu H., Man G.C., Zhang T., Chu K.O., Chu C.Y., Cheng J.T., Li G., He Y.X., Qin L., et al

Low Plasma Marine N-3 Polyunsaturated Fatty Acids are Associated With Increased Risk of Cardiovascular Events in Patients Treated With Maintenance Hemodialysis