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The organism is ubiquitous with childhood acquisition seemingly being the role and may last for years or decades however, it is difficult to ascertain when infection occurs clinically hence seroprevalence data are the source of information of rates both in geographically and demographically diverse populations [2, 52, 58, 59, 60]

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The miRNAs and long non-coding RNAs (lncRNAs) and extracellular vesicles (EVs) induced by viral factors MiRNAs and lncRNAs are two pivotal classes of regulatory RNAs

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