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Through multi-targeted approaches, they aim to disrupt the vicious cycle of mutual reinforcement between CKD and sarcopenia, providing a robust theoretical foundation and practical direction for improving patient outcomes

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However, a large number of studies have been remaining at the cellular level to validate the target sites of these derivatives, while the studies of verifying their drug efficacy and conducting safety evaluations at the animal level are relatively scarce, which affects the potential for drug development

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