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The gap between effective and ineffective use comes down to understanding that the dihexa half life dictates dosing frequency, but therapeutic outcomes are determined by what happens at the synaptic level during those brief exposure windows

Wang et al., 2011) and synaptogenesis (see preliminary studies below)

The product was diluted with 0.5 M sodium phosphate buffer to a final concentration of ~515 M

66 KokkalaP.MpakaliA.MauvaisF.-X.PapakyriakouA.DaskalakiI.PetropoulouI.et al (2016)

However, for the peptide Pep-B, a study was conducted prior to this one where it was shown that the effective dose was 2.5 and 5 g/ml Pep-B instead of the maximum dose to stimulate hDPSCs cell proliferation