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Researchers frequently study both to compare copper peptide class activity

The findings highlight the potential of spirulina as a nutraceutical intervention for managing neurodegenerative disorders such as Parkinsons disease through its antioxidant and cytoprotective properties ( Spirulina platensis as a robust nutraceutical candidate capable of modulating oxidative stress, apoptosis, and lipid metabolism in diverse biological systems

Importantly, commonly used in vitro BBB models, such as transwell systems and endothelial cell lines including RBE4, bEnd.3, and hCMEC/D3 monolayers, have important limitations, as they may overpredict permeability and do not fully recapitulate key in vivo BBB features, including physiological shear stress and multicellular neurovascular architecture (Katt and Shusta, 2020)

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