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Alzheimers dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: Implications for early detection and therapy

Heatmaps were then created to show the correlations (with corresponding p-values) between the groups and the metabolite and microbial taxa modules

Pentose Phosphate Pathway Lets run it back and start with a quick overview of the PPP

A distinct biochemical component also contributes significantly to RBC senescence in parallel with mechanical degradation

Oxidative stress is proposed as a major pathogenic mechanism in Alzheimers disease (Liu et al., 2004