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however, the mechanism is poorly understood [131, 132]

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Membrane disruption occurs via ion-mediated depolarization and physical contact, while ROS generation causes oxidative damage

In Swiss male albino rats co-supplemented with 7501,000 g/kg/b.w./day AFB1 and 2 mg/0.2 ml olive oil/day, the outcomes showed that curcumin could ameliorate the AFB1-toxic effects in reproduction system of rats by improving caput and cauda epididymis weight and enzymatic activity (422)