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It is known that tobacco smoke can interact with drugs both through pharmacokinetic and pharmacodynamic mechanisms [24]

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"According to the government's forecasts," recalls the president, Gabriele Melluso, "the increase in prices to the public for cigarettes and tobacco will guarantee 1.47 billion euro in additional revenue over the three-year period

The primary component of cigarettes is nicotine, which significantly contributes to the development of peptic ulcers by disrupting the balance between offensive and protective elements in the gastrointestinal tract [14]

This epidemic makes the need for quitting even more immediate and compelling