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Effects of Smokeless Tobacco Use on the Upper Gastrointestinal Tract Mucosa: Gross and Histopathological Changes PMC Gastroesophageal reflux disease (#GERD) symptoms frequently include chronic heartburn (a burning chest pain), bitter acid regurgitation, and upper abdominal pain, often worsening after eating, bending, or lying down. Other common symptoms include Does tobacco affect the digestive system Progress Gastro Care Smoking and GERD: Effects, link, and more Tobacco and Digestive System Dr. Abhishek Mitra

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